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PVAR3D
vanB - Q06893
Model based on:
Entry features
Model PirFile Alignment Superimposition Procheck
GENE vanB
DESCRIPTION D-alanine--D-lactate ligase
ORGANISM Enterococcus faecalis (strain ATCC 700802 / V583)
TAXONOMY Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;Enterococcus.
UNIPROT Q06893
Template 1e4e A
Cross-references
STRING 226185.EF2294
REFSEQ NP_815951.1; NC_004668.1; WP_002368691.1; NZ_KE136528.1
PFAM PF01820 - Dala_Dala_lig_N; PF07478 - Dala_Dala_lig_C
PATRIC fig|226185.45.peg.1238
KEGG efa:EF2294
EMBL AE016830; AAO82021.1; L06138; NOT_ANNOTATED_CDS; L15304; AAA24785.1; U00456; AAC43217.1; U35369; AAB05627.1
BioCyc/EcoCyc/MetaCyc EFAE226185:G1G0C-2250-MONOMER; MetaCyc:MONOMER-15464
EC 6.1.2.1;

Gene Ontology
Molecular Function GO ID Term Evidence
GO:0005524 F:ATP binding IEA
GO:0008716 F:D-alanine-D-alanine ligase activity IEA
GO:0046872 F:metal ion binding IEA
Biological Process GO ID Term Evidence
GO:0008360 P:regulation of cell shape IEA
GO:0009252 P:peptidoglycan biosynthetic process IEA
GO:0046677 P:response to antibiotic IEA
GO:0071555 P:cell wall organization IEA
Cellular Component GO ID Term Evidence
GO:0005737 C:cytoplasm IEA
GO:0005886 C:plasma membrane IEA
Mutation panel
Mutation Phenotype Reference Map mutation on Model
A106C

(non-resistant)

In strain: SF300 		PMID:NA 105
E153D

(non-resistant)

In strain: SF300 		PMID:NA 152
S185G

(non-resistant)

In strain: SF300 		PMID:NA 184
I258T

(non-resistant)

In strain: SF300 		PMID:NA 257
Sequence
Multiple sequence alignment Not Available
MSA Mutation Not Available