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PVAR3D
Probable arabinosyltransferase A - P9WNL9
Model based on:
Entry features
Model PirFile Alignment Superimposition Procheck MSA
GENE Probable arabinosyltransferase A
ORGANISM Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
TAXONOMY Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;Mycobacterium; Mycobacterium tuberculosis complex.
UNIPROT P9WNL9
Template 3byw B
RESISTANCE ethambutol
Cross-references
STRING 83332.Rv3794
REFSEQ NP_218311.1; NC_000962.3; WP_003899696.1; NZ_KK339374.1
PFAM PF04602 - Arabinose_trans; PF14896 - Arabino_trans_C
KEGG mtu:Rv3794
EMBL AL123456; CCP46623.1; U68480; AAC45280.1
EC 2.4.2.-;
CHEMBL CHEMBL1877

Gene Ontology
Molecular Function GO ID Term Evidence
GO:0052636 F:arabinosyltransferase activity IDA
Biological Process GO ID Term Evidence
GO:0046677 P:response to antibiotic IEA
GO:0071555 P:cell wall organization IEA
GO:0071766 P:Actinobacterium-type cell wall biogenesis IMP
Cellular Component GO ID Term Evidence
GO:0005829 C:cytosol IDA
GO:0005886 C:plasma membrane IDA
GO:0005576 C:extracellular region IGI
GO:0005887 C:integral component of plasma membrane IDA
Mutation panel
Mutation Phenotype Reference Map mutation on Model
A201T ethambutol PMID:10639358 -
G321S ethambutol PMID:10639358 -
G350D ethambutol PMID:10639358 -
A462V ethambutol PMID:10639358 -
D833A ethambutol PMID:10639358 -
P913S ethambutol PMID:10639358 -
Sequence
Multiple sequence alignment
MSA Mutation
Variant Position in MSA
P913S 941