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PVAR3D
50S ribosomal protein L4 - P44345
Model based on:
Entry features
Model PirFile Alignment Superimposition Procheck MSA
GENE 50S ribosomal protein L4
ORGANISM Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
TAXONOMY Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;Pasteurellaceae; Haemophilus.
UNIPROT P44345
Template 4u20 E
RESISTANCE macrolide
Cross-references
STRING 71421.HI0778
REFSEQ NP_438937.1; NC_000907.1; WP_005652369.1
PFAM PF00573 - Ribosomal_L4
PATRIC fig|71421.8.peg.817
KEGG hin:HI0778
EMBL L42023; AAC22437.1; U37797; AAB41511.1
BioCyc/EcoCyc/MetaCyc HINF71421:G1GJ1-818-MONOMER
Drugbank DB01321 - Josamycin

Gene Ontology
Molecular Function GO ID Term Evidence
GO:0003723 F:RNA binding IBA
GO:0003735 F:structural constituent of ribosome IBA
GO:0019843 F:rRNA binding IEA
Biological Process GO ID Term Evidence
GO:0006412 P:translation IBA
GO:0006355 P:regulation of transcription, DNA-templated IEA
GO:0046677 P:response to antibiotic IEA
GO:0006353 P:DNA-templated transcription, termination IEA
GO:0006417 P:regulation of translation IEA
Cellular Component GO ID Term Evidence
GO:0022626 C:cytosolic ribosome IBA
Mutation panel
Mutation Phenotype Reference Map mutation on Model
T64K macrolide PMID:NA 64
G65D macrolide PMID:NA 65
A69S macrolide PMID:NA 69
T82I macrolide PMID:NA 82
Sequence
Multiple sequence alignment
MSA Mutation
Variant Position in MSA
T82I 83