Enoyl-[acyl-carrier-protein] reductase [NADH] FabI - P16657
Model based on:
Entry features
| GENE | Enoyl-[acyl-carrier-protein] reductase [NADH] FabI | |
|---|---|---|
| DESCRIPTION | NADH-dependent enoyl-ACP reductase | |
| ORGANISM | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) | |
| TAXONOMY | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;Enterobacteriaceae; Salmonella. | |
| UNIPROT | P16657 | |
| Template | 1qsg C | |
| RESISTANCE | diazaborine |
Cross-references
| STRING | 99287.STM1700 |
|---|---|
| REFSEQ | NP_460659.1; NC_003197.2; WP_000506505.1 |
| PATRIC | fig|99287.12.peg.1794 |
| KEGG | stm:STM1700 |
| EMBL | AE006468; AAL20618.1; M31806; AAA27059.1 |
| BioCyc/EcoCyc/MetaCyc | SENT99287:G1FZD-1716-MONOMER |
| EC | 1.3.1.9; |
| Active site | 146 146 Proton acceptor; 156 156 Proton acceptor |
Gene Ontology
| Molecular Function | GO ID | Term | Evidence |
|---|---|---|---|
| GO:0004318 | F:enoyl-[acyl-carrier-protein] reductase (NADH) activity | ISS | |
| GO:0016631 | F:enoyl-[acyl-carrier-protein] reductase activity | IEA | |
| Biological Process | GO ID | Term | Evidence |
| GO:0009102 | P:biotin biosynthetic process | ISS | |
| GO:0030497 | P:fatty acid elongation | ISS | |
| GO:0046677 | P:response to antibiotic | IEA | |
| GO:0051289 | P:protein homotetramerization | ISS |
Mutation panel
| Mutation | Phenotype | Reference | Map mutation on Model |
|---|---|---|---|
| G93S | diazaborine | PMID:NA | 92 |
Sequence
Multiple sequence alignment
MSA Mutation
| Variant | Position in MSA |
|---|---|
| G93S | 95 |