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PVAR3D
DNA gyrase subunit B - P0A4L9
Model based on:
Entry features
Model PirFile Alignment Superimposition Procheck MSA
GENE DNA gyrase subunit B
ORGANISM Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
TAXONOMY Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;Streptococcus.
UNIPROT P0A4L9
Template 4i3h A
RESISTANCE novobiocin
Cross-references
REFSEQ WP_000134039.1; NZ_AKVY01000001.1
PFAM PF02518 - HATPase_c; PF00204 - DNA_gyraseB; PF00986 - DNA_gyraseB_C; PF01751 - Toprim
KEGG spn:SP_0806
EMBL AE005672; AAK74943.1; X83917; CAA58771.1
EC 5.99.1.3
Drugbank DB01044 - Gatifloxacin
CHEMBL CHEMBL1075021

Gene Ontology
Molecular Function GO ID Term Evidence
GO:0003677 F:DNA binding IEA
GO:0003918 F:DNA topoisomerase type II (ATP-hydrolyzing) activity IEA
GO:0005524 F:ATP binding IEA
GO:0046872 F:metal ion binding IEA
Biological Process GO ID Term Evidence
GO:0006261 P:DNA-dependent DNA replication IEA
GO:0006265 P:DNA topological change IEA
GO:0046677 P:response to antibiotic IEA
Cellular Component GO ID Term Evidence
GO:0005694 C:chromosome IEA
GO:0005737 C:cytoplasm IEA
Mutation panel
Mutation Phenotype Reference Map mutation on Model
S127L novobiocin PMID:NA 102
Sequence
Multiple sequence alignment
MSA Mutation
Variant Position in MSA
S127L 129