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PVAR3D
DNA-directed RNA polymerase subunit beta - O86094
Model based on:
Entry features
Model PirFile Alignment Superimposition Procheck MSA
GENE DNA-directed RNA polymerase subunit beta
DESCRIPTION RNA polymerase subunit beta
ORGANISM Legionella pneumophila
TAXONOMY Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;Legionellaceae; Legionella.
UNIPROT O86094
Template 4ljz I
RESISTANCE rifampicin
Cross-references
REFSEQ WP_011945543.1; NZ_PQXA01000007.1
PFAM PF10385 - RNA_pol_Rpb2_45; PF04561 - RNA_pol_Rpb2_2; PF04560 - RNA_pol_Rpb2_7; PF04563 - RNA_pol_Rpb2_1; PF04565 - RNA_pol_Rpb2_3; PF00562 - RNA_pol_Rpb2_6
EMBL AF087812; AAC69338.1; AF101273; AAC95361.1
EC 2.7.7.6

Gene Ontology
Molecular Function GO ID Term Evidence
GO:0003677 F:DNA binding IEA
GO:0003899 F:DNA-directed 5'-3' RNA polymerase activity IEA
GO:0032549 F:ribonucleoside binding IEA
Biological Process GO ID Term Evidence
GO:0006351 P:transcription, DNA-templated IEA
GO:0046677 P:response to antibiotic IEA
Mutation panel
Mutation Phenotype Reference Map mutation on Model
S537P rifampicin PMID:NA 528
H541Y rifampicin PMID:NA 532
R544H rifampicin PMID:NA 535
Sequence
Multiple sequence alignment
MSA Mutation
Variant Position in MSA
R544H 552