DNA-directed RNA polymerase subunit beta - O52271
Model based on:
Entry features
| GENE | DNA-directed RNA polymerase subunit beta | |
|---|---|---|
| DESCRIPTION | RNA polymerase subunit beta | |
| ORGANISM | Rickettsia prowazekii (strain Madrid E) | |
| TAXONOMY | Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;Rickettsiaceae; Rickettsieae; Rickettsia; typhus group. | |
| UNIPROT | O52271 | |
| Template | 4kn4 C | |
| RESISTANCE | rifampicin |
Cross-references
| STRING | 272947.RP140 |
|---|---|
| REFSEQ | NP_220531.1; NC_000963.1; WP_010886216.1 |
| PFAM | PF10385 - RNA_pol_Rpb2_45; PF04560 - RNA_pol_Rpb2_7; PF04563 - RNA_pol_Rpb2_1; PF04561 - RNA_pol_Rpb2_2; PF04565 - RNA_pol_Rpb2_3; PF00562 - RNA_pol_Rpb2_6 |
| PATRIC | fig|272947.5.peg.142 |
| KEGG | rpr:RP140 |
| EMBL | AF034531; AAC38354.1; AF076437; AAF22439.1; AJ235270; CAA14608.1 |
| BioCyc/EcoCyc/MetaCyc | RPRO272947:G1GT0-142-MONOMER |
| EC | 2.7.7.6 |
Gene Ontology
| Molecular Function | GO ID | Term | Evidence |
|---|---|---|---|
| GO:0003677 | F:DNA binding | IEA | |
| GO:0003899 | F:DNA-directed 5'-3' RNA polymerase activity | IEA | |
| GO:0032549 | F:ribonucleoside binding | IEA | |
| Biological Process | GO ID | Term | Evidence |
| GO:0006351 | P:transcription, DNA-templated | IEA | |
| GO:0046677 | P:response to antibiotic | IEA |
Mutation panel
| Mutation | Phenotype | Reference | Map mutation on Model |
|---|---|---|---|
| R546K | rifampicin | PMID:NA | 531 |
Sequence
Multiple sequence alignment
MSA Mutation
| Variant | Position in MSA |
|---|---|
| R546K | 585 |