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PVAR3D
Beta-lactamase CTX-M-4 - O33807
Model based on:
Entry features
Model PirFile Alignment Superimposition Procheck MSA
GENE Beta-lactamase CTX-M-4
DESCRIPTION Cefotaximase 4
ORGANISM Salmonella typhimurium
TAXONOMY Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;Enterobacteriaceae; Salmonella.
UNIPROT O33807
Template 2zq8 A
RESISTANCE ceftriaxone and aztreonam
Cross-references
REFSEQ WP_032489025.1; NG_048990.1
KEGG ag:CAA74573
EMBL Y14156; CAA74573.1
EC 3.5.2.6;
Active site 73 73 Acyl-ester intermediate

Gene Ontology
Molecular Function GO ID Term Evidence
GO:0008800 F:beta-lactamase activity IEA
Biological Process GO ID Term Evidence
GO:0030655 P:beta-lactam antibiotic catabolic process IEA
GO:0046677 P:response to antibiotic IEA
Mutation panel
Mutation Phenotype Reference Map mutation on Model
R277N ceftriaxone and aztreonam PMID:NA 247
Sequence
Multiple sequence alignment
MSA Mutation
Variant Position in MSA
R277N 288