fusA - ARO:3003735-CAG39573
Model based on:
Entry features
| GENE | fusA |
|---|---|
| ORGANISM | Staphylococcus aureus subsp. aureus MRSA252 |
| TAXONOMY | Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;Staphylococcus. |
| UNIPROT | Q6GJC1 |
| NCBI | CAG39573 |
| ARO term | ARO:3003735 |
| Template | 2xex B |
| RESISTANCE | fusidic acid |
Cross-references
| REFSEQ | WP_000090315.1; NC_002952.2 | |
|---|---|---|
| PFAM | PF00009 - GTP_EFTU; PF00679 - EFG_C; PF03144 - GTP_EFTU_D2; PF03764 - EFG_IV | |
| KEGG | sar:SAR0552 | |
| EMBL | BX571856; CAG39573.1 | |
| NUCLEOTIDE BINDING | 135 138 GTP; 17 24 GTP; 81 85 GTP |
Gene Ontology
| Molecular Function | GO ID | Term | Evidence |
|---|---|---|---|
| GO:0003746 | F:translation elongation factor activity | IEA | |
| GO:0003924 | F:GTPase activity | IEA | |
| GO:0005525 | F:GTP binding | IEA | |
| Cellular Component | GO ID | Term | Evidence |
| GO:0005737 | C:cytoplasm | IEA |
Mutation panel
Sequence
Multiple sequence alignment
MSA Mutation
| Variant | Position in MSA |
|---|---|
| A376V | 376 |
| A67T;P406L | 67;406 |
| A70V;A160V;H457Y | 70;160;457 |
| D189V;L430S | 189;430 |
| D434N | 434 |
| F441Y | 441 |
| F652S;Y654N | 652;654 |
| F88L | 88 |
| G451V | 451 |
| G452C | 452 |
| G452C;R659L | 452;659 |
| G452S | 452 |
| G452V | 452 |
| H457Q | 457 |
| H457Y | 457 |
| H457Y;S416F | 457;416 |
| L456F | 456 |
| L461F | 461 |
| L461K | 461 |
| L461S | 461 |
| M453I | 453 |
| P404L | 404 |
| P404Q | 404 |
| P406L | 406 |
| Q115L | 115 |
| R464C | 464 |
| R464H | 464 |
| R464L | 464 |
| R464S | 464 |
| T387I;E449K | 387;449 |
| T436I | 436 |
| V407F | 407 |
| V90A | 90 |
| V90I | 90 |
| V90I;H457Q;L461K;A655V | 90;457;461;655 |