tetR - ARO:3003479-CAD09823.1
Model based on:
Entry features
| GENE | tetR |
|---|---|
| ORGANISM | Salmonella enterica subsp. enterica serovar Typhi str. CT18 |
| TAXONOMY | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;Enterobacteriaceae; Salmonella. |
| UNIPROT | Q9S455 |
| NCBI | CAD09823.1 |
| ARO term | ARO:3003479 |
| Template | 3zqi B |
| RESISTANCE | glycylcycline; tetracycline |
Cross-references
| STRING | 220341.HCM1.243 |
|---|---|
| REFSEQ | NP_058294.1; NC_002305.1; NP_569430.1; NC_003384.1; WP_001322387.1; NZ_PZMA01000050.1 |
| PFAM | PF00440 - TetR_N; PF02909 - TetR_C |
| PATRIC | fig|220341.7.peg.5258 |
| KEGG | sty:HCM1.243 |
| EMBL | AF223162; AAF68935.1; AF250878; AAF69919.1; AL513383; CAD09823.1; AY150213; AAN77729.1 |
Gene Ontology
| Molecular Function | GO ID | Term | Evidence |
|---|---|---|---|
| GO:0003677 | F:DNA binding | IEA | |
| Biological Process | GO ID | Term | Evidence |
| GO:0006351 | P:transcription, DNA-templated | IEA | |
| GO:0045892 | P:negative regulation of transcription, DNA-templated | IEA | |
| GO:0046677 | P:response to antibiotic | IEA |
Mutation panel
| Mutation | Phenotype | Reference | Map mutation on Model |
|---|---|---|---|
| H64Y | resistant | PMID:3062183 | 60 |
| N82H | resistant | PMID:3062183 | 78 |
| T103I | resistant | PMID:3062183 | 99 |
Sequence
Multiple sequence alignment
MSA Mutation
| Variant | Position in MSA |
|---|---|
| H64Y | 64 |
| N82H | 82 |
| T103I | 103 |