gidB - ARO:3003470-CCP46748.1
Model based on:
Entry features
| GENE | gidB | |
|---|---|---|
| DESCRIPTION | 16S rRNA 7-methylguanosine methyltransferase | |
| ORGANISM | Mycobacterium tuberculosis H37Rv | |
| TAXONOMY | Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;Mycobacterium; Mycobacterium tuberculosis complex. | |
| UNIPROT | P9WGW9 | |
| NCBI | CCP46748.1 | |
| ARO term | ARO:3003470 | |
| Template | 1jsx A | |
| RESISTANCE | aminoglycoside; streptomycin |
Cross-references
| STRING | 83332.Rv3919c |
|---|---|
| REFSEQ | NP_218436.2; NC_000962.3; WP_003899763.1; NZ_KK339374.1 |
| PFAM | PF02527 - GidB |
| PATRIC | fig|83332.111.peg.4365 |
| KEGG | mtu:Rv3919c; mtv:RVBD_3919c |
| EMBL | AL123456; CCP46748.1; HQ611141; ADU15870.1 |
| EC | 2.1.1.- |
Gene Ontology
| Molecular Function | GO ID | Term | Evidence |
|---|---|---|---|
| GO:0070043 | F:rRNA (guanine-N7-)-methyltransferase activity | IBA | |
| Biological Process | GO ID | Term | Evidence |
| GO:0070476 | P:rRNA (guanine-N7)-methylation | IBA | |
| Cellular Component | GO ID | Term | Evidence |
| GO:0005829 | C:cytosol | IBA | |
| GO:0005886 | C:plasma membrane | IDA |
Mutation panel
Sequence
Multiple sequence alignment
MSA Mutation
| Variant | Position in MSA |
|---|---|
| A134E | 158 |
| A138E | 162 |
| A183E | 207 |
| A183T | 207 |
| A200E | 224 |
| D67H | 91 |
| G117E | 141 |
| G164C | 188 |
| G30R | 54 |
| G71V | 95 |
| H48Y | 72 |
| I55S | 79 |
| L49F | 73 |
| L79F | 103 |
| N52T | 76 |
| P75S | 99 |
| P84C | 108 |
| P84L | 108 |
| Q127P | 151 |
| R47Q | 71 |
| S70R | 94 |
| V188G | 212 |
| V188M | 212 |
| W148R | 172 |
| W45C | 69 |
| W45S | 69 |