soxR - ARO:3003382-NP_458564.1
Model based on:
Entry features
| GENE | soxR |
|---|---|
| ORGANISM | Salmonella enterica subsp. enterica serovar Typhi str. CT18 |
| TAXONOMY | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;Enterobacteriaceae; Salmonella. |
| UNIPROT | P0A2R1 |
| NCBI | NP_458564.1 |
| ARO term | ARO:3003382 |
| Template | 2zhg A |
| RESISTANCE | atp; cephalosporin; fluoroquinolone; glycylcycline; penam; phenicol; rifamycin; tetracycline; triclosan |
Cross-references
| STRING | 220341.STY4464 |
|---|---|
| REFSEQ | NP_458564.1; NC_003198.1; WP_000412686.1; NZ_QAVO01000008.1 |
| PFAM | PF00376 - MerR; PF09278 - MerR-DNA-bind |
| PATRIC | fig|220341.7.peg.4565 |
| KEGG | stt:t4172; sty:STY4464 |
| EMBL | AE014613; AAO71636.1; AL513382; CAD09250.1 |
Gene Ontology
| Molecular Function | GO ID | Term | Evidence |
|---|---|---|---|
| GO:0003677 | F:DNA binding | IEA | |
| GO:0046872 | F:metal ion binding | IEA | |
| GO:0051537 | F:2 iron, 2 sulfur cluster binding | IEA | |
| Biological Process | GO ID | Term | Evidence |
| GO:0006351 | P:transcription, DNA-templated | IEA | |
| GO:0006355 | P:regulation of transcription, DNA-templated | IEA | |
| GO:0006979 | P:response to oxidative stress | IEA |
Mutation panel
| Mutation | Phenotype | Reference | Map mutation on Model |
|---|---|---|---|
| G121D | resistant | PMID:11302826 | 112 |
| R20H | resistant | PMID:19104017 | 11 |
Sequence
Multiple sequence alignment
MSA Mutation
| Variant | Position in MSA |
|---|---|
| G121D | 121 |
| R20H | 20 |