acrR - ARO:3003373-ABR75897.1
Model based on:
Entry features
| GENE | acrR |
|---|---|
| ORGANISM | Klebsiella pneumoniae subsp. pneumoniae MGH 78578 |
| TAXONOMY | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;Enterobacteriaceae; Klebsiella. |
| UNIPROT | A6T5M6 |
| NCBI | ABR75897.1 |
| ARO term | ARO:3003373 |
| Template | 3bcg A |
| RESISTANCE | cephalosporin; fluoroquinolone; glycylcycline; penam; phenicol; rifamycin; tetracycline; triclosan |
Cross-references
| STRING | 272620.KPN_00445 |
|---|---|
| REFSEQ | WP_002892080.1; NC_009648.1 |
| PFAM | PF00440 - TetR_N; PF08361 - TetR_C_2 |
| KEGG | kpn:KPN_00445 |
| EMBL | CP000647; ABR75897.1 |
Gene Ontology
| Molecular Function | GO ID | Term | Evidence |
|---|---|---|---|
| GO:0003677 | F:DNA binding | IEA | |
| Biological Process | GO ID | Term | Evidence |
| GO:0006351 | P:transcription, DNA-templated | IEA | |
| GO:0006355 | P:regulation of transcription, DNA-templated | IEA |
Mutation panel
| Mutation | Phenotype | Reference | Map mutation on Model |
|---|---|---|---|
| M109I | resistant | PMID:PMID in progress (single) | 104 |
| V165I | resistant | PMID:PMID in progress (single) | 160 |
| Y114F | resistant | PMID:PMID in progress (single) | 109 |
Sequence
Multiple sequence alignment
MSA Mutation
| Variant | Position in MSA |
|---|---|
| M109I | 109 |
| V165I | 165 |
| Y114F | 114 |