nalC - ARO:3000818-NP_252410.1
Model based on:
Entry features
| GENE | nalC |
|---|---|
| ORGANISM | Pseudomonas aeruginosa PAO1 |
| TAXONOMY | Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;Pseudomonadaceae; Pseudomonas. |
| UNIPROT | Q9HXS0 |
| NCBI | NP_252410.1 |
| ARO term | ARO:3000818 |
| Template | 3dew A |
| RESISTANCE | aminocoumarin; carbapenem; cephalosporin; cephamycin; diaminopyrimidine; fluoroquinolone; macrolide; monobactam; penam; penem; peptide; phenicol; sulfonamide; tetracycline |
Cross-references
| STRING | 208964.PA3721 |
|---|---|
| REFSEQ | NP_252410.1; NC_002516.2; WP_003113837.1 |
| PFAM | PF00440 - TetR_N |
| PATRIC | fig|208964.12.peg.3892 |
| KEGG | pae:PA3721 |
| EMBL | AE004091; AAG07108.1 |
| BioCyc/EcoCyc/MetaCyc | PAER208964:G1FZ6-3791-MONOMER |
Gene Ontology
| Molecular Function | GO ID | Term | Evidence |
|---|---|---|---|
| GO:0000976 | F:transcription regulatory region sequence-specific DNA binding | IDA | |
| GO:0003700 | F:DNA-binding transcription factor activity | IBA | |
| GO:0044212 | F:transcription regulatory region DNA binding | IDA | |
| Biological Process | GO ID | Term | Evidence |
| GO:0006351 | P:transcription, DNA-templated | IEA | |
| GO:0032410 | P:negative regulation of transporter activity | IMP | |
| GO:0034763 | P:negative regulation of transmembrane transport | IMP | |
| GO:0045892 | P:negative regulation of transcription, DNA-templated | IMP | |
| Cellular Component | GO ID | Term | Evidence |
| GO:0005829 | C:cytosol | IBA |
Mutation panel
| Mutation | Phenotype | Reference | Map mutation on Model |
|---|---|---|---|
| A186T | resistant | PMID:27412168 | - |
| G71E | resistant | PMID:27060003 | 58 |
| R97G | resistant | PMID:27412168 | 84 |
| S209R | resistant | PMID:27060003 | - |
Sequence
Multiple sequence alignment Not Available
MSA Mutation Not Available