MexS - ARO:3000813-ADT64081.1
Model based on:
Entry features
| GENE | MexS |
|---|---|
| ORGANISM | Pseudomonas aeruginosa PAK |
| TAXONOMY | Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;Pseudomonadaceae; Pseudomonas. |
| UNIPROT | E7DZ84 |
| NCBI | ADT64081.1 |
| ARO term | ARO:3000813 |
| Template | 3jyn A |
| RESISTANCE | diaminopyrimidine; fluoroquinolone; phenicol |
Cross-references
| REFSEQ | WP_003103552.1; NZ_QJPG01000001.1 |
|---|---|
| PFAM | PF08240 - ADH_N |
| PATRIC | fig|287.1477.peg.2421 |
| EMBL | CP012901; ALV78663.1; CP028162; AVR83075.1; CP029745; AWS90160.1; HQ433550; ADT64081.1; KT454971; ALI58734.1; LT969520; SOV29407.1; NFFZ01000006; OTI61712.1; NMRQ01000010; OZO18542.1; QFRL01000046; PWH87676.1; QHLE01000022; PXA56104.1 |
| EC | 1.6.5.5 |
Gene Ontology
| Molecular Function | GO ID | Term | Evidence |
|---|---|---|---|
| GO:0003960 | F:NADPH:quinone reductase activity | IEA |
Mutation panel
| Mutation | Phenotype | Reference | Map mutation on Model |
|---|---|---|---|
| A166P | resistant | PMID:26833155 | 166 |
| C245G | resistant | PMID:26833155 | 245 |
| D44E | resistant | PMID:26833155 | 44 |
| F185L | resistant | PMID:26833155 | 185 |
| F253L | resistant | PMID:26833155 | 253 |
| L263Q | resistant | PMID:26833155 | 263 |
| L270Q | resistant | PMID:26833155 | 270 |
| S60F | resistant | PMID:26833155 | 60 |
| S60P | resistant | PMID:PMID in progress (single) | 60 |
| V104A | resistant | PMID:26833155 | 104 |
| V73A | resistant | PMID:26833155 | 73 |
Sequence
Multiple sequence alignment Not Available
MSA Mutation Not Available