por - ARO:3000464-AAB57788.1
Model based on:
Entry features
| GENE | por |
|---|---|
| ORGANISM | Neisseria gonorrhoeae |
| TAXONOMY | Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales;Neisseriaceae; Neisseria. |
| UNIPROT | P95351 |
| NCBI | AAB57788.1 |
| ARO term | ARO:3000464 |
| Template | 3vy8 X |
| RESISTANCE | carbapenem; cephalosporin; cephamycin; monobactam; penam; penem; tetracycline |
Cross-references
| PFAM | PF00267 - Porin_1 |
|---|---|
| EMBL | U75641; AAB57788.1 |
Gene Ontology
| Molecular Function | GO ID | Term | Evidence |
|---|---|---|---|
| GO:0015288 | F:porin activity | IEA | |
| Biological Process | GO ID | Term | Evidence |
| GO:0006811 | P:ion transport | IEA | |
| Cellular Component | GO ID | Term | Evidence |
| GO:0009279 | C:cell outer membrane | IEA | |
| GO:0046930 | C:pore complex | IEA |
Mutation panel
| Mutation | Phenotype | Reference | Map mutation on Model |
|---|---|---|---|
| A121D | resistant | PMID:12183233 | 102 |
| G120D | resistant | PMID:12183233 | 101 |
| G120K | resistant | PMID:12183233 | 101 |
| G120P,A121P | resistant | PMID:12183233 | 101; 102 |
| G120R,A121H | resistant | PMID:12183233 | 101; 102 |
Sequence
Multiple sequence alignment
MSA Mutation
| Variant | Position in MSA |
|---|---|
| A121D | 121 |
| G120D | 120 |
| G120K | 120 |
| G120P;A121P | 120;121 |
| G120R;A121H | 120;121 |