cfr - Q9FBG4
No structure available
Entry features
| GENE | cfr | |
|---|---|---|
| DESCRIPTION | 23S rRNA (adenine(2503)-C(8))-methyltransferase | |
| ORGANISM | Staphylococcus sciuri | |
| TAXONOMY | Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;Staphylococcus. | |
| UNIPROT | Q9FBG4 |
Cross-references
| REFSEQ | NP_899167.1; NC_005076.1; WP_001010505.1; NG_047631.1 |
|---|---|
| PFAM | PF04055 - Radical_SAM |
| KEGG | ag:CAE18142 |
| EMBL | AJ249217; CAC04525.1; AJ579365; CAE18142.1 |
| BioCyc/EcoCyc/MetaCyc | MetaCyc:MONOMER-16695 |
| EC | 2.1.1.224 |
| Active site | 91 91 Proton acceptor; 338 338 S-methylcysteine intermediate |
Gene Ontology
| Molecular Function | GO ID | Term | Evidence |
|---|---|---|---|
| GO:0016433 | F:rRNA (adenine) methyltransferase activity | IEA | |
| GO:0019843 | F:rRNA binding | IEA | |
| GO:0046872 | F:metal ion binding | IEA | |
| GO:0051539 | F:4 iron, 4 sulfur cluster binding | IEA | |
| Biological Process | GO ID | Term | Evidence |
| GO:0046677 | P:response to antibiotic | IEA | |
| GO:0070475 | P:rRNA base methylation | IEA | |
| Cellular Component | GO ID | Term | Evidence |
| GO:0005737 | C:cytoplasm | IEA |
Mutation panel
| Mutation | Phenotype | Reference |
|---|---|---|
| C110A |
(non-resistant) No change in activity |
PMID:NA |
Sequence
Multiple sequence alignment Not Available
MSA Mutation Not Available