Probable arabinosyltransferase C - P9WNL5
Structure
Entry features
| GENE | Probable arabinosyltransferase C |
|---|---|
| ORGANISM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
| TAXONOMY | Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;Mycobacterium; Mycobacterium tuberculosis complex. |
| UNIPROT | P9WNL5 |
| RESISTANCE | ethambutol |
Cross-references
| STRING | 83332.Rv3793 |
|---|---|
| REFSEQ | NP_218310.1; NC_000962.3; WP_003901726.1; NZ_KK339374.1 |
| PFAM | PF04602 - Arabinose_trans; PF14896 - Arabino_trans_C |
| KEGG | mtu:Rv3793 |
| EMBL | AL123456; CCP46622.1; U68480; AAC45279.1 |
| BioCyc/EcoCyc/MetaCyc | MetaCyc:G185E-8089-MONOMER |
| EC | 2.4.2.-; |
Gene Ontology
| Molecular Function | GO ID | Term | Evidence |
|---|---|---|---|
| GO:0052636 | F:arabinosyltransferase activity | IMP | |
| Biological Process | GO ID | Term | Evidence |
| GO:0009247 | P:glycolipid biosynthetic process | IMP | |
| GO:0046677 | P:response to antibiotic | IEA | |
| GO:0071555 | P:cell wall organization | IEA | |
| GO:0071766 | P:Actinobacterium-type cell wall biogenesis | IEA | |
| Cellular Component | GO ID | Term | Evidence |
| GO:0005829 | C:cytosol | IDA | |
| GO:0005886 | C:plasma membrane | IEA | |
| GO:0016021 | C:integral component of membrane | IEA |
Mutation panel
| Mutation | Phenotype | Reference |
|---|---|---|
| N394D | ethambutol | PMID:10639358 |
| R738Q | ethambutol | PMID:10639358 |
Sequence
Multiple sequence alignment
MSA Mutation
| Variant | Position in MSA |
|---|---|
| R738Q | 738 |