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PVAR3D
Enoyl-[acyl-carrier-protein] reductase [NADH] - P42829
Model based on:
Entry features
Model PirFile Alignment Superimposition Procheck MSA
GENE Enoyl-[acyl-carrier-protein] reductase [NADH]
DESCRIPTION FAS-II enoyl-ACP reductase
ORGANISM Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
TAXONOMY Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;Mycolicibacterium.
UNIPROT P42829
Template 2aq8 A
RESISTANCE isoniazid
Cross-references
STRING 246196.MSMEG_3151
REFSEQ WP_003894540.1; NZ_CP009494.1; YP_887466.1; NC_008596.1
PTM Is phosphorylated in vivo (PubMed:20864541)
PATRIC fig|246196.19.peg.3112
KEGG msb:LJ00_15670; msg:MSMEI_3070; msm:MSMEG_3151
EMBL CP000480; ABK73247.1; CP001663; AFP39534.1; U02530; AAC43211.1
EC 1.3.1.9

Gene Ontology
Molecular Function GO ID Term Evidence
GO:0004318 F:enoyl-[acyl-carrier-protein] reductase (NADH) activity IEA
GO:0016631 F:enoyl-[acyl-carrier-protein] reductase activity IEA
Biological Process GO ID Term Evidence
GO:0006633 P:fatty acid biosynthetic process IEA
GO:0046677 P:response to antibiotic IEA
Cellular Component GO ID Term Evidence
GO:0005576 C:extracellular region IEA
GO:0005618 C:cell wall IEA
Mutation panel
Mutation Phenotype Reference Map mutation on Model
S94A isoniazid PMID:8284673 92
V238F isoniazid PMID:NA 236
Sequence
Multiple sequence alignment
MSA Mutation
Variant Position in MSA
S94A 94
V238F 238