menA - ARO:3003917-YP_499533.1
No structure available
Entry features
| GENE | menA |
|---|---|
| ORGANISM | Staphylococcus aureus subsp. aureus NCTC 8325 |
| TAXONOMY | Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;Staphylococcus. |
| UNIPROT | Q2FZM0 |
| NCBI | YP_499533.1 |
| ARO term | ARO:3003917 |
| RESISTANCE | Lysocin E; lysocin; peptide |
Cross-references
| STRING | 93061.SAOUHSC_00980 | |
|---|---|---|
| REFSEQ | WP_000070966.1; NZ_LS483365.1; YP_499533.1; NC_007795.1 | |
| PFAM | PF01040 - UbiA | |
| PATRIC | fig|93061.5.peg.901 | |
| KEGG | sao:SAOUHSC_00980 | |
| EMBL | CP000253; ABD30105.1 | |
| BioCyc/EcoCyc/MetaCyc | SAUR93061:G1G5Y-923-MONOMER | |
| EC | 2.5.1.74 | |
| Catalytic activity | An all-trans-polyprenyl diphosphate + 1,4- dihydroxy-2-naphthoate = a demethylmenaquinol + diphosphate + CO(2); ECO:0000256| HAMAP-Rule:MF_01937 | |
| PATHWAY | Quinol/quinone metabolism; menaquinone biosynthesis; |
Gene Ontology
| Molecular Function | GO ID | Term | Evidence |
|---|---|---|---|
| GO:0004659 | F:prenyltransferase activity | IBA | |
| GO:0046428 | F:1,4-dihydroxy-2-naphthoate octaprenyltransferase activity | IEA | |
| Biological Process | GO ID | Term | Evidence |
| GO:0009234 | P:menaquinone biosynthetic process | IBA | |
| GO:0032194 | P:ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate | IBA | |
| GO:0042371 | P:vitamin K biosynthetic process | IBA | |
| Cellular Component | GO ID | Term | Evidence |
| GO:0005887 | C:integral component of plasma membrane | IEA |
Mutation panel
| Mutation | Phenotype | Reference |
|---|---|---|
| G33D | resistant | PMID:25485686 |
Sequence
Multiple sequence alignment Not Available
MSA Mutation Not Available