mexZ - ARO:3003709-NP_250710.1
Structure
Entry features
| GENE | mexZ |
|---|---|
| ORGANISM | Pseudomonas aeruginosa PAO1 |
| TAXONOMY | Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;Pseudomonadaceae; Pseudomonas. |
| UNIPROT | G3XCU9 |
| NCBI | NP_250710.1 |
| ARO term | ARO:3003709 |
| RESISTANCE | acridine dye; aminoglycoside; carbapenem; cephalosporin; cephamycin; fluoroquinolone; macrolide; penam; phenicol; tetracycline |
Cross-references
| STRING | 208964.PA2020 |
|---|---|
| REFSEQ | NP_250710.1; NC_002516.2; WP_003088626.1 |
| PFAM | PF00440 - TetR_N; PF08361 - TetR_C_2 |
| PATRIC | fig|208964.12.peg.2105 |
| KEGG | pae:PA2020 |
| EMBL | AE004091; AAG05408.1 |
Gene Ontology
| Molecular Function | GO ID | Term | Evidence |
|---|---|---|---|
| GO:0000976 | F:transcription regulatory region sequence-specific DNA binding | IDA | |
| GO:0001217 | F:bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding | IDA | |
| GO:0043565 | F:sequence-specific DNA binding | IDA | |
| GO:0044212 | F:transcription regulatory region DNA binding | IDA | |
| Biological Process | GO ID | Term | Evidence |
| GO:0006351 | P:transcription, DNA-templated | IEA | |
| GO:0006355 | P:regulation of transcription, DNA-templated | IDA | |
| GO:0032410 | P:negative regulation of transporter activity | IMP | |
| GO:0034763 | P:negative regulation of transmembrane transport | IMP | |
| GO:0045892 | P:negative regulation of transcription, DNA-templated | IDA | |
| Cellular Component | GO ID | Term | Evidence |
| GO:0005829 | C:cytosol | IBA | |
| GO:0032993 | C:protein-DNA complex | IDA |
Mutation panel
| Mutation | Phenotype | Reference |
|---|---|---|
| G195E | resistant | PMID:15336398 |
| G46S | resistant | PMID:15336398 |
| Q10Z | resistant | PMID:15336398 |
| V44A | resistant | PMID:15336398 |
Sequence
Multiple sequence alignment Not Available
MSA Mutation Not Available