embB - ARO:3003326-CCP46624.1
Model based on:
Entry features
| GENE | embB |
|---|---|
| ORGANISM | Mycobacterium tuberculosis H37Rv |
| TAXONOMY | Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;Mycobacterium; Mycobacterium tuberculosis complex. |
| UNIPROT | P9WNL7 |
| NCBI | CCP46624.1 |
| ARO term | ARO:3003326 |
| Template | 3pty A |
| RESISTANCE | ethambutol; polyamine |
Cross-references
| STRING | 83332.Rv3795 |
|---|---|
| REFSEQ | NP_218312.1; NC_000962.3; WP_003901728.1; NZ_KK339374.1 |
| PFAM | PF04602 - Arabinose_trans; PF14896 - Arabino_trans_C |
| KEGG | mtu:Rv3795 |
| EMBL | AL123456; CCP46624.1; U68480; AAC45281.1 |
| BioCyc/EcoCyc/MetaCyc | MetaCyc:G185E-8091-MONOMER |
| EC | 2.4.2.-; |
Gene Ontology
| Molecular Function | GO ID | Term | Evidence |
|---|---|---|---|
| GO:0052636 | F:arabinosyltransferase activity | IEA | |
| Biological Process | GO ID | Term | Evidence |
| GO:0046677 | P:response to antibiotic | IEA | |
| GO:0071555 | P:cell wall organization | IEA | |
| GO:0071766 | P:Actinobacterium-type cell wall biogenesis | IEA | |
| Cellular Component | GO ID | Term | Evidence |
| GO:0005618 | C:cell wall | IDA | |
| GO:0005886 | C:plasma membrane | IDA | |
| GO:0016021 | C:integral component of membrane | IEA |
Mutation panel
Sequence
Multiple sequence alignment
MSA Mutation
| Variant | Position in MSA |
|---|---|
| Q497K | 502 |
| D328Y | 333 |
| D328G | 333 |
| F330V | 335 |
| G406A | 411 |
| L413P | 418 |
| S297A | 302 |
| D299E | 304 |
| M306L | 311 |
| M306V | 311 |
| M306I | 311 |
| M306T | 311 |
| D311H | 316 |
| L239P | 244 |
| D240H | 245 |
| Y334H | 339 |
| A356V | 361 |
| A357S | 362 |
| E368A | 373 |
| P375A | 380 |
| E378A | 383 |
| S380R | 385 |
| P397Q | 402 |
| N399H | 404 |
| G406S | 411 |
| G406C | 411 |
| G406D | 411 |
| P446H | 451 |
| R460C | 465 |
| I465D | 470 |
| R469P | 474 |
| R471P | 476 |
| Q497R | 502 |
| G745D | 753 |
| D959A | 968 |
| M1000R | 1009 |
| D1024N | 1033 |
| E504Q | 509 |
| R507G | 512 |
| A314G;Y322C | 319;327 |
| Y319C | 324 |
| Y333C | 338 |
| Y319N | 324 |
| T630I | 635 |