pgsA - ARO:3003323-WP_001025093
No structure available
Entry features
| GENE | pgsA |
|---|---|
| ORGANISM | Staphylococcus aureus |
| TAXONOMY | Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;Staphylococcus. |
| UNIPROT | A0A0E1VHX4 |
| NCBI | WP_001025093 |
| ARO term | ARO:3003323 |
| RESISTANCE | daptomycin; peptide |
Cross-references
| REFSEQ | WP_001025093.1; NZ_GG697985.1 |
|---|---|
| PFAM | PF01066 - CDP-OH_P_transf |
| EMBL | AASB02000234; EES93041.1 |
| EC | 2.7.8.5 |
Gene Ontology
| Molecular Function | GO ID | Term | Evidence |
|---|---|---|---|
| GO:0008444 | F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity | IEA | |
| Biological Process | GO ID | Term | Evidence |
| GO:0008654 | P:phospholipid biosynthetic process | IEA | |
| Cellular Component | GO ID | Term | Evidence |
| GO:0016021 | C:integral component of membrane | IEA |
Mutation panel
| Mutation | Phenotype | Reference |
|---|---|---|
| A64V | resistant | PMID:22238576 |
| K66R | resistant | PMID:22238576 |
| S177F | resistant | PMID:22238576 |
| V59N | resistant | PMID:22238576 |
Sequence
Multiple sequence alignment
MSA Mutation
| Variant | Position in MSA |
|---|---|
| A64V | 64 |
| K66R | 66 |
| S177F | 177 |
| V59N | 59 |