The table contains the entries for bacterial proteins resistant to a drug or set of drugs by single aminoacid mutation
and also a set of entries with mutations not involved in antibiotic resistance mechanisms.
Search in the table by ID: (ARO, NCBI, UNIPROT), Gene, Genus/Organism, Drug.
| Id | Structure | Gene | Organism | Miscellaneous (Resistance to drug/non-resistant description) |
|---|---|---|---|---|
| ARO:3003817-AJF82744.1 | model | gyrA | Acinetobacter baumannii | fluoroquinolone, nybomycin, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3003709-NP_250710.1 | 2WUI | mexZ | Pseudomonas aeruginosa PAO1 | macrolide, fluoroquinolone, aminoglycoside, carbapenem, cephalosporin, cephamycin, penam, tetracycline, acridine dye, phenicol |
| ARO:3003310-AKJ52802.1 | model | parC | Mycoplasma hominis | fluoroquinolone, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3003374-CAC35723.1 | model | acrR | Enterobacter aerogenes | fluoroquinolone, cephalosporin, glycylcycline, penam, tetracycline, rifamycin, phenicol, triclosan |
| ARO:3003383-NP_463130.1 | model | soxS | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | fluoroquinolone, atp, monobactam, carbapenem, cephalosporin, glycylcycline, cephamycin, penam, tetracycline, rifamycin, phenicol, triclosan, penem |
| ARO:3003379-ACH50230.1 | model | ramR | Salmonella enterica subsp. enterica serovar Agona str. SL483 | fluoroquinolone, cephalosporin, glycylcycline, penam, tetracycline, rifamycin, phenicol, triclosan |
| ARO:3003305-WP_004025678.1 | model | gyrB | Ureaplasma urealyticum | fluoroquinolone, aminocoumarin, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3000464-AAB57788.1 | model | por | Neisseria gonorrhoeae | monobactam, carbapenem, cephalosporin, cephamycin, penam, tetracycline, penem |
| ARO:3003380-ABR76005.1 | model | ramR | Klebsiella pneumoniae subsp. pneumoniae MGH 78578 | fluoroquinolone, cephalosporin, glycylcycline, penam, tetracycline, rifamycin, phenicol, triclosan |
| ARO:3003370-NP_417798.1 | 4PC3; 2HCJ; 4PC7; 1ETU; 3U2Q; 4V69; 5JBQ; 1D8T; 1MJ1; 5I4R; 5I4Q; 3EP2; 5UYQ; 5UYP; 1EFC; 2FX3; 2HDN; 5UYK; 5UYM; 5UYL; 5UYN; 4G5G; 3U6B; 3EQ3; 3U6K; 4Q7J; 3EQ4 | EF-Tu | Escherichia coli str. K-12 substr. MG1655 | elfamycin, enacyloxin IIa |
| ARO:3003323-WP_001025093 | no data | pgsA | Staphylococcus aureus | peptide, daptomycin |
| ARO:3003390-NP_415449.1 | 5NUQ; 1BT9; 4JFB; 3FYX; 3K1B; 3O0E; 1GFN; 1GFO; 4D5U; 1GFM; 3HWB; 2ZLD; 5NUO; 1GFP; 1GFQ; 1HXX; 1HXU; 1HXT; 1OPF; 2OMF; 3HW9; 5NUR; 1MPF; 2ZFG; 3POX; 4GCS; 4GCP; 4GCQ; 4LSI; 4LSH; 3K19; 3POQ; 4LSF; 3POU; 4LSE | ompF | Escherichia coli str. K-12 substr. MG1655 | monobactam, carbapenem, cephalosporin, cephamycin, penam, penem, cefepime |
| ARO:3003386-WP_000764731.1 | 1AJ0; 1AJ2; 1AJZ | folP | Proteobacteria | sulfonamide, sulfone, sulfadiazine, sulfadimidine, sulfadoxine, sulfamethoxazole, sulfisoxazole, sulfacetamide, mafenide, sulfasalazine, sulfamethizole |
| ARO:3003294-AAC75291.1 | 1ZI0; 4ELY; 1AB4; 2Y3P; 1X75; 3NUH | gyrA | Escherichia coli str. K-12 substr. MG1655 | fluoroquinolone, nybomycin, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin, triclosan |
| ARO:3003316-WP_000195296.1 | 3FV5; 1S16; 1S14; 4HZ0 | parE | Proteobacteria | fluoroquinolone, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3003074-YP_500802.1 | no data | cls | Staphylococcus aureus subsp. aureus NCTC 8325 | peptide, daptomycin |
| ARO:3003327-AFN51819.1 | model | embC | Mycobacterium tuberculosis H37Rv | polyamine, ethambutol |
| ARO:3003306-WP_004236715.1 | model | gyrB | Morganella | fluoroquinolone, aminocoumarin, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3003939-NP_462089.1 | model | parC | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | fluoroquinolone, ciprofloxacin, nalidixic acid |
| ARO:3003470-CCP46748.1 | model | gidB | Mycobacterium tuberculosis H37Rv | aminoglycoside, streptomycin |
| ARO:3003304-CAC29513.1 | model | gyrB | Mycobacterium leprae TN | fluoroquinolone, aminocoumarin, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3003895-NP_249870.1 | model | PhoP | Pseudomonas aeruginosa PAO1 | macrolide, peptide, colistin A, colistin B |
| ARO:3003686-NP_249649.1 | 2ODJ; 4FOZ; 3SY7 | oprD | Pseudomonas aeruginosa PAO1 | monobactam, carbapenem, cephalosporin, cephamycin, penam, penem, imipenem |
| ARO:3003285-YP_039996.1 | model | rpoB | Staphylococcus aureus subsp. aureus MRSA252 | peptide, rifamycin, rifampin, rifaximin, rifabutin, rifapentine |
| ARO:3003309-WP_010891786.1 | model | parC | Ureaplasma parvum | fluoroquinolone, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3003761-AGQ48857.1 | model | eatAv | Enterococcus faecium | lincosamide, streptogramin, pleuromutilin, lincosamide antibiotic, streptogramin antibiotic |
| ARO:3003296-YP_039483.1 | model | gyrA | Staphylococcus aureus subsp. aureus MRSA252 | fluoroquinolone, nybomycin, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3003387-AAL97684.1 | model | folP | Streptococcus pyogenes MGAS8232 | sulfonamide, sulfone, sulfadiazine, sulfadimidine, sulfadoxine, sulfamethoxazole, sulfisoxazole, sulfacetamide, mafenide, sulfasalazine, sulfamethizole |
| ARO:3004060-NP_253290.1 | no data | NfxB | Pseudomonas aeruginosa PAO1 | macrolide, fluoroquinolone, cephalosporin, penam, tetracycline, aminocoumarin, diaminopyrimidine, phenicol, aminoglycoside |
| ARO:3003317-NP_462096.1 | model | parE | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | fluoroquinolone, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3003307-NP_462735.1 | model | gyrB | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | fluoroquinolone, aminocoumarin, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3003295-CCP42728.1 | 3UC1; 5BTL; 5BTN; 5BTI; 3ILW; 5BTA; 5BTG; 5BTF; 4G3N; 5BTC; 5BS8; 5BTD; 3IFZ | gyrA | Mycobacterium tuberculosis H37Rv | fluoroquinolone, nybomycin, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3003926-NP_461214.1 | model | gyrA | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | fluoroquinolone, nybomycin, ciprofloxacin, nalidixic acid, triclosan |
| ARO:3003301-YP_039482.1 | model | gyrB | Staphylococcus aureus subsp. aureus MRSA252 | aminocoumarin, novobiocin, clorobiocin, coumermycin A1 |
| ARO:3003794-CAG39047 | model | walK | Staphylococcus aureus subsp. aureus MRSA252 | peptide, daptomycin |
| ARO:3003311-AAK74984.1 | 3RAD; 3RAE; 3RAF; 2NOV; 4I3H; 3KSB; 3KSA; 3LTN; 4Z53; 4JUO; 3K9F; 4Z3O; 3FOF; 3FOE; 4Z4Q; 4KPF; 4KPE; 4KOE | parC | Streptococcus pneumoniae TIGR4 | fluoroquinolone, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3003889-CDJ72593 | model | GlpT | Escherichia coli str. K-12 substr. MC4100 | fosfomycin |
| ARO:3003438-YP_006374661.1 | model | EF-Tu | Enterococcus faecium DO | elfamycin, GE2270A |
| ARO:3003298-CAC29514.1 | model | gyrA | Mycobacterium leprae TN | fluoroquinolone, nybomycin, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3003807-NP_414997.1 | 2QOP; 3BCG | acrR | Escherichia coli str. K-12 substr. MG1655 | fluoroquinolone, cephalosporin, glycylcycline, penam, tetracycline, rifamycin, phenicol, triclosan |
| ARO:3000813-ADT64081.1 | model | MexS | Pseudomonas aeruginosa PAK | fluoroquinolone, diaminopyrimidine, phenicol |
| ARO:3003511-NP_418486.1 | model | soxS | Escherichia coli str. K-12 substr. MG1655 | fluoroquinolone, atp, monobactam, carbapenem, cephalosporin, glycylcycline, cephamycin, penam, tetracycline, rifamycin, phenicol, triclosan, penem |
| ARO:3003459-CAA55486.1 | model | gyrB | Mycobacterium tuberculosis H37Ra | fluoroquinolone, aminocoumarin, enoxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3003308-AAC76055.1 | 4MN4; 1ZVU; 1ZVT | parC | Escherichia coli str. K-12 substr. MG1655 | fluoroquinolone, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3003041-AFC91828.1 | model | PBP1a | Streptococcus pneumoniae | monobactam, carbapenem, cephalosporin, cephamycin, penam, amoxicillin |
| ARO:3003312-YP_040772.1 | model | parC | Staphylococcus aureus subsp. aureus MRSA252 | fluoroquinolone, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3004153-NP_217280.1 | 4FOG; 4FQS; 3QJ7; 4FOA; 4FOX | thyA | Mycobacterium tuberculosis H37Rv | para-aminosalicylic acid, aminosalicylate |
| ARO:3003385-AAK11270.1 | model | omp36 | Enterobacter aerogenes | monobactam, carbapenem, cephalosporin, cephamycin, penam, penem |
| ARO:3003369-AAN82549.1 | model | EF-Tu | Escherichia coli CFT073 | elfamycin, pulvomycin |
| ARO:3003043-AFC91898.1 | model | PBP2x | Streptococcus pneumoniae | monobactam, carbapenem, cephalosporin, cephamycin, penam, amoxicillin |
| ARO:3004334-NP_461214.1 | model | gyrA | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | fluoroquinolone, nybomycin, triclosan |
| ARO:3000506-NP_249115.1 | 4ZZL; 3ECH; 1LNW; 3MEX | mexR | Pseudomonas aeruginosa PAO1 | macrolide, fluoroquinolone, monobactam, carbapenem, cephalosporin, cephamycin, penam, tetracycline, peptide, aminocoumarin, diaminopyrimidine, sulfonamide, phenicol, penem |
| ARO:3003818-ALJ89624.1 | model | parC | Acinetobacter baumannii | fluoroquinolone, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3003373-ABR75897.1 | model | acrR | Klebsiella pneumoniae subsp. pneumoniae MGH 78578 | fluoroquinolone, cephalosporin, glycylcycline, penam, tetracycline, rifamycin, phenicol, triclosan |
| ARO:3003315-YP_040771.1 | model | parE | Staphylococcus aureus subsp. aureus MRSA252 | fluoroquinolone, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3003937-NP_273462.1 | model | PBP2 | Neisseria meningitidis MC58 | monobactam, carbapenem, cephalosporin, cephamycin, penam, ceftriaxone, cefixime |
| ARO:3003453-AFN51820.1 | model | embA | Mycobacterium tuberculosis H37Rv | polyamine, ethambutol |
| ARO:3003297-AAL82403.1 | model | gyrA | Bartonella bacilliformis | fluoroquinolone, nybomycin, enoxacin, ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, ofloxacin, trovafloxacin, grepafloxacin, sparfloxacin, pefloxacin |
| ARO:3000814-NP_251182.1 | model | MexT | Pseudomonas aeruginosa PAO1 | fluoroquinolone, diaminopyrimidine, phenicol |
| ARO:3003751-NP_415372.1 | 1F5V | nfsA | Escherichia coli str. K-12 substr. MG1655 | nitrofuran, nitrofurantoin |
| ARO:3003684-NP_251858.1 | model | gyrA | Pseudomonas aeruginosa PAO1 | fluoroquinolone, nybomycin, ciprofloxacin, levofloxacin, ofloxacin, sparfloxacin, pefloxacin, sitafloxacin |
| ARO:3003458-AAK48336.1 | model | ethA | Mycobacterium tuberculosis CDC1551 | isoniazid, ethionamide |
| ARO:3003792-NP_816529.1 | model | liaR | Enterococcus faecalis V583 | peptide, daptomycin |
| ARO:3003077-AAO82601.1 | no data | liaF | Enterococcus faecalis V583 | peptide, daptomycin |
| ARO:3003319-ADJ67256 | model | mprF | Staphylococcus aureus | peptide, daptomycin |
| ARO:3003392-NP_216424.1 | 1SJ2; 4C50; 1SFZ; 4C51; 2CCA; 2CCD | katG | Mycobacterium tuberculosis H37Rv | isoniazid |
| ARO:3003092-ALL09868.1 | no data | cls | Enterococcus faecium | peptide, daptomycin |
| ARO:3003381-AAC77033.1 | 2ZHH; 2ZHG | soxR | Escherichia coli str. K-12 substr. MG1655 | fluoroquinolone, atp, cephalosporin, glycylcycline, penam, tetracycline, rifamycin, phenicol, triclosan |
| ARO:3003890-CDJ73208 | model | UhpT | Escherichia coli str. K-12 substr. MC4100 | fosfomycin |
| ARO:3003784-CCE36834 | model | murA | Mycobacterium tuberculosis UT205 | fosfomycin |
| ARO:3003359-CAA67349.1 | model | EF-Tu | Streptomyces cinnamoneus | elfamycin, kirromycin |
| ARO:3003303-BAE77595.1 | 4WUC; 4ZVI; 4HYP; 1AJ6; 3G7E; 5L3J; 3NUH; 4KFG; 4WUD; 4PU9; 4PRV; 4XTJ; 1EI1; 5MMP; 4WUB; 4DUH; 1KZN; 5MMO; 4PRX; 5MMN | gyrB | Escherichia coli str. K-12 substr. W3110 | aminocoumarin, novobiocin, clorobiocin, coumermycin A1 |
| ARO:3003776-CAG41169.1 | model | murA | Staphylococcus aureus subsp. aureus MRSA252 | fosfomycin |
| ARO:3004446-NP_439290 | model | PBP3 | Haemophilus influenzae Rd KW20 | monobactam, carbapenem, cephalosporin, cephamycin, penam |
| ARO:3004097-AQA08261.1 | model | CdsA | Streptococcus oralis | peptide, daptomycin |
| ARO:3003378-AAC74603.2 | 4JBA; 3VOD; 3VOE; 1JGS; 5H3R; 3VB2 | marR | Escherichia coli str. K-12 substr. MG1655 | fluoroquinolone, cephalosporin, glycylcycline, penam, tetracycline, rifamycin, phenicol, triclosan |
| ARO:3003288-NP_312937.1 | model | rpoB | Escherichia coli O157:H7 str. Sakai | peptide, rifamycin, rifampin, rifaximin, rifabutin, rifapentine |
| ARO:3003314-BAA11086.1 | model | parE | Staphylococcus aureus RN4220 | aminocoumarin, novobiocin, clorobiocin, coumermycin A1 |
| ARO:3003395-AAK44936.1 | model | rpsL | Mycobacterium tuberculosis CDC1551 | aminoglycoside, streptomycin |
| ARO:3003382-NP_458564.1 | model | soxR | Salmonella enterica subsp. enterica serovar Typhi str. CT18 | fluoroquinolone, atp, cephalosporin, glycylcycline, penam, tetracycline, rifamycin, phenicol, triclosan |
| ARO:3003465-AAK48268.1 | model | embB | Mycobacterium tuberculosis CDC1551 | rifamycin, polyamine, rifampin |
| ARO:3003917-YP_499533.1 | no data | menA | Staphylococcus aureus subsp. aureus NCTC 8325 | peptide, lysocin, Lysocin E |
| ARO:3003737-ADL24064.1 | model | fusE | Staphylococcus aureus subsp. aureus JKD6159 | fusidic acid |
| ARO:3003368-AAA50993.1 | 4PC3; 2HCJ; 4PC7; 1ETU; 3U2Q; 4V69; 5JBQ; 1D8T; 1MJ1; 5I4R; 5I4Q; 3EP2; 5UYQ; 5UYP; 1EFC; 2FX3; 2HDN; 5UYK; 5UYM; 5UYL; 5UYN; 4G5G; 3U6B; 3EQ3; 3U6K; 4Q7J; 3EQ4 | EF-Tu | Escherichia coli | elfamycin, kirromycin-like antibiotics |
| ARO:3003797-WP_002356022 | model | YybT | Enterococcus | peptide, daptomycin |
| ARO:3004184-NP_217187.1 | 6DE5; 4XT8; 4XT4; 4XT5; 4XT6; 4XT7; 4XRB | ribD | Mycobacterium tuberculosis H37Rv | para-aminosalicylic acid, aminosalicylate |
| ARO:3003325-CDO45096.1 | model | embB | Mycobacterium bovis AF2122/97 | polyamine, ethambutol |
| ARO:3003995-YP_001086469.1 | model | gyrA | Clostridium difficile 630 | fluoroquinolone, nybomycin |
| ARO:3003042-NP_359110.1 | 2WAF; 2WAD; 2WAE | PBP2b | Streptococcus pneumoniae R6 | monobactam, carbapenem, cephalosporin, cephamycin, penam, amoxicillin |
| ARO:3004135-NP_214855.1 | no data | iniB | Mycobacterium tuberculosis H37Rv | polyamine, ethambutol |
| ARO:3003302-WP_005768149.1 | model | gyrB | Bartonella bacilliformis KC583 | aminocoumarin, novobiocin, clorobiocin, coumermycin A1 |
| ARO:3003893-CDJ73205 | model | UhpA | Escherichia coli str. K-12 substr. MC4100 | fosfomycin |
| ARO:3003283-CCP43410.1 | 5UHF; 5UHG; 5UHD; 5UHE; 5UHB; 5UHC; 5UHA; 5UH6; 5UH5; 6FBV; 4KBJ; 4KBM; 5UH8; 5UH9 | rpoB | Mycobacterium tuberculosis H37Rv | peptide, rifamycin, rifampin, rifaximin, rifabutin, rifapentine |
| ARO:3004059-NP_253290.1 | no data | NfxB | Pseudomonas aeruginosa PAO1 | macrolide, fluoroquinolone, cephalosporin, penam, tetracycline, aminocoumarin, diaminopyrimidine, phenicol, aminoglycoside |
| ARO:3003941-NP_708834.1 | model | parC | Shigella flexneri 2a str. 301 | fluoroquinolone, nalidixic acid, norfloxacin |
| ARO:3003574-AJF83452.1 | model | LpxC | Acinetobacter baumannii | peptide, colistin |
| ARO:3004145-EGP45233.1 | model | AxyZ | Achromobacter insuavis AXX-A | macrolide, fluoroquinolone, aminoglycoside, cephalosporin |
| ARO:3004045-NP_415804.1 | 1MFP; 1I30; 1DFI; 1DFH; 3PJF; 1LXC; 1DFG; 5CG1; 3PJE; 1LX6; 1QG6; 1D8A; 1C14; 3PJD; 4JX8; 5CFZ; 5CG2; 1QSG; 1I2Z; 4JQC; 2FHS | fabI | Escherichia coli str. K-12 substr. MG1655 | isoniazid, triclosan |
| ARO:3003291-YP_039997.1 | model | rpoC | Staphylococcus aureus subsp. aureus MRSA252 | peptide, daptomycin |
| ARO:3003284-CAC30845.1 | model | rpoB | Mycobacterium leprae | peptide, rifamycin, rifampin, rifaximin, rifabutin, rifapentine |
| ARO:3003585-CDO13981.1 | model | PhoP | Klebsiella pneumoniae | macrolide, peptide, colistin |
| ARO:3003735-CAG39573 | model | fusA | Staphylococcus aureus subsp. aureus MRSA252 | fusidic acid |
| ARO:3000818-NP_252410.1 | model | nalC | Pseudomonas aeruginosa PAO1 | macrolide, fluoroquinolone, monobactam, carbapenem, cephalosporin, cephamycin, penam, tetracycline, peptide, aminocoumarin, diaminopyrimidine, sulfonamide, phenicol, penem |
| ARO:3000819-NP_252264.1 | 5H9T; 5DAJ | nalD | Pseudomonas aeruginosa PAO1 | macrolide, fluoroquinolone, monobactam, carbapenem, cephalosporin, cephamycin, penam, tetracycline, peptide, aminocoumarin, diaminopyrimidine, sulfonamide, phenicol, penem |
| ARO:3003899-CDJ72759 | model | PtsI | Escherichia coli str. K-12 substr. MC4100 | fosfomycin |
| ARO:3003729-CAA52296.1 | 1QU3; 1FFY; 1QU2 | ileS | Staphylococcus aureus | mupirocin |
| ARO:3003451-CCP43073.1 | no data | iniC | Mycobacterium tuberculosis H37Rv | polyamine, ethambutol |
| ARO:3003790-CUX99269.1 | no data | liaF | Enterococcus faecium | peptide, daptomycin |
| ARO:3003940-NP_708120.1 | 2Y3P | gyrA | Shigella flexneri 2a str. 301 | fluoroquinolone, nybomycin, nalidixic acid, norfloxacin |
| ARO:3003778-WP_038583059 | model | ndh | Mycobacterium smegmatis | isoniazid |
| ARO:3003760-AEA93051.1 | no data | cls | Enterococcus faecalis OG1RF | peptide, daptomycin |
| ARO:3003455-CCP44023.1 | 2FEZ; 2FF4 | embR | Mycobacterium tuberculosis H37Rv | polyamine, ethambutol |
| ARO:3003326-CCP46624.1 | model | embB | Mycobacterium tuberculosis H37Rv | polyamine, ethambutol |
| ARO:3003779-CAL71877.1 | no data | ndh | Mycobacterium bovis BCG str. Pasteur 1173P2 | isoniazid |
| ARO:3003685-NP_253654.1 | model | parE | Pseudomonas aeruginosa PAO1 | fluoroquinolone |
| ARO:3003448-CCP43072.1 | no data | iniA | Mycobacterium tuberculosis H37Rv | polyamine, ethambutol |
| ARO:3003463-CCP45025.1 | 5LD8; 2WGD; 2WGE; 2WGF; 2WGG | kasA | Mycobacterium tuberculosis H37Rv | isoniazid, triclosan |
| ARO:3003582-NP_253464.1 | model | basR | Pseudomonas aeruginosa PAO1 | peptide |
| ARO:3003461-CCP44620.1 | model | ndh | Mycobacterium tuberculosis H37Rv | isoniazid |
| ARO:3003078-AFK58562.1 | model | liaR | Enterococcus faecium DO | peptide, daptomycin |
| ARO:3003788-BAA85265 | no data | pgsA | Bacillus subtilis | peptide, daptomycin |
| ARO:3003287-YP_039996.1 | model | rpoB | Staphylococcus aureus subsp. aureus MRSA252 | peptide, rifamycin |
| ARO:3003970-AAN62561.1 | model | D-Ala-D-Ala ligase | Enterococcus gallinarum | glycopeptide |
| ARO:3003805-WP_002389492.1 | model | gshF | Enterococcus | peptide, daptomycin |
| ARO:3004049-NP_415611.1 | 1Q7C; 1Q7B; 1I01 | fabG | Escherichia coli str. K-12 substr. MG1655 | triclosan |
| ARO:3003393-CCP44244.1 | 5CP8; 2PR2; 3OF2; 5COQ; 5CPB; 5CPF; 4DRE; 2IDZ; 3FNH; 3FNE; 3FNG; 3FNF; 2AQ8; 3OEW; 3OEY; 2NSD; 5UGU; 5UGT; 5UGS; 1ENY; 4DTI; 4UVG; 4UVE; 4UVD; 4UVI; 4UVH; 2AQH; 2AQI; 2AQK; 4QXM; 4BQP; 4BQR; 1BVR; 1ENZ; 6GH1; 1P45; 1P44; 4BGE; 4OIM; 4BGI; 2B35; 2B37; 2B36; 4OXN; 4OXK; 5G0T; 5G0U; 5G0V; 5G0W; 4OXY; 5G0S; 4U0K; 2H9I; 2NTJ; 4R9S; 4R9R; 5MTR; 5MTP; 5MTQ; 2X22; 4OYR; 2X23; 4D0R; 4D0S; 2IED; 2IEB; 4U0J; 4DQU; 5JFO; 2NV6; 4BII; 4OHU; 1ZID; 4TZK; 4TRJ; 4TRN; 4TRO; 4TZT; 4TRM; 5OIN; 5OIM; 5OIL; 5OIF; 4COD; 5OIT; 2IE0 | inhA | Mycobacterium tuberculosis H37Rv | isoniazid, triclosan |
| ARO:3003702-BAA37152.1 | model | gyrA | Pseudomonas aeruginosa | fluoroquinolone, nybomycin |
| ARO:3003928-YP_207769.1 | model | gyrA | Neisseria gonorrhoeae FA 1090 | fluoroquinolone, nybomycin |
| ARO:3003974-AER05434.1 | model | gyrA | Cutibacterium acnes subsp. defendens ATCC 11828 | fluoroquinolone, nybomycin |
| ARO:3004157-NP_216963.1 | 2VOS; 2VOR | folC | Mycobacterium tuberculosis H37Rv | para-aminosalicylic acid, aminosalicylate |
| ARO:3003777-NP_212606.2 | model | murA | Borrelia burgdorferi B31 | fosfomycin |
| ARO:3003775-AIL15701 | model | murA | Escherichia coli ATCC 25922 | fosfomycin |
| ARO:3003902-CAG39240 | no data | UhpT | Staphylococcus aureus subsp. aureus MRSA252 | fosfomycin |
| ARO:3003924-WP_014065640.1 | model | gyrA | Haemophilus parainfluenzae | fluoroquinolone, nybomycin |
| ARO:3003769-ADJ67256.1 | model | mprF | Staphylococcus aureus | peptide, defensin |
| ARO:3003789-YP_002344422.1 | model | gyrA | Campylobacter jejuni subsp. jejuni NCTC 11168 | fluoroquinolone, nybomycin, ciprofloxacin |
| ARO:3003389-CAC29732.1 | model | folP | Mycobacterium leprae TN | sulfonamide, dapsone, sulfone |
| ARO:3003479-CAD09823.1 | model | tetR | Salmonella enterica subsp. enterica serovar Typhi str. CT18 | glycylcycline, tetracycline |
| ARO:3003357-WP_009887863.1 | model | EF-Tu | Clostridium difficile | elfamycin |
| ARO:3003929-YP_208330.1 | model | parC | Neisseria gonorrhoeae FA 1090 | fluoroquinolone |
| ARO:3003445-AAK46002.1 | 5EOV | tlyA | Mycobacterium tuberculosis CDC1551 | aminoglycoside, streptomycin |
| ARO:3003079-AFK58561.1 | model | liaS | Enterococcus faecium DO | peptide, daptomycin |
| ARO:3003394-CCP44816.1 | 3PL1 | pncA | Mycobacterium tuberculosis H37Rv | pyrazinamide |
| ARO:3003791-AAO82600.1 | model | liaS | Enterococcus faecalis V583 | peptide, daptomycin |
| ARO:3003900-CDJ73082 | no data | CyaA | Escherichia coli str. K-12 substr. MC4100 | fosfomycin |
| ARO:3003931-EEK14408.1 | model | gyrA | Capnocytophaga gingivalis ATCC 33624 | fluoroquinolone, nybomycin |
| ARO:3003573-AJF82049.1 | model | LpxA | Acinetobacter baumannii | peptide, colistin |
| ARO:3004335-AAC75291.1 | 1ZI0; 4ELY; 1AB4; 2Y3P; 1X75; 3NUH | gyrA | Escherichia coli str. K-12 substr. MG1655 | fluoroquinolone, nybomycin, triclosan |
| ARO:3003925-WP_041918279.1 | model | parC | Haemophilus parainfluenzae | fluoroquinolone |
| ARO:3003896-NP_249871.1 | model | PhoQ | Pseudomonas aeruginosa PAO1 | macrolide, peptide, colistin |
| ARO:3003930-YP_208874.1 | model | rpsJ | Neisseria gonorrhoeae FA 1090 | tetracycline |
| ARO:3003361-AAB39605.1 | model | EF-Tu | Planobispora rosea | elfamycin |
| ARO:3003901-CAG39357 | model | GlpT | Staphylococcus aureus subsp. aureus MRSA252 | fosfomycin |
| ARO:3003028-CAB12062.1 | model | lmrA | Bacillus subtilis subsp. subtilis str. 168 | lincosamide |
| A8C927 | 3P2K; 3P2I; 3MTE; 3P2E; 3PB3; 4OX9 | 16S rRNA | Escherichia coli | kanamycin |
| P61182 | model | 50S ribosomal protein L22 | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) | antibiotic resistance |
| P37870 | 2LY7 | DNA-directed RNA polymerase subunit beta | Bacillus subtilis (strain 168) | streptolydigan, rifampicin |
| P9WG45 | 3ZKB; 5BTL; 5BTN; 5BTI; 3ZKD; 5BTD; 5BTG; 5BTF; 5BTA; 5BTC; 5BS8; 3IG0; 3M4I; 2ZJT; 3ZM7 | DNA gyrase subunit B | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | novobiocin, aminopyrazinamides, fluoroquinolone |
| P25920 | 3MQ2 | 16S rRNA | Streptoalloteichus tenebrarius (strain ATCC 17920 / DSM 40477 / NCIB 11028) (Streptomyces tenebrarius) | kanamycin |
| P44360 | model | 50S ribosomal protein L22 | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) | macrolide |
| Q59517 | 2CC1 | Beta-lactamase | Mycobacterium fortuitum | amoxicillin |
| P36556 | model | Transcriptional regulatory protein BasR | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) | polymyxin b |
| P9WNL9 | model | Probable arabinosyltransferase A | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ethambutol |
| P44345 | model | 50S ribosomal protein L4 | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) | macrolide |
| P0A2Y8 | no data | ATP synthase subunit a | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) | optochin |
| P0C563 | model | 30S ribosomal protein S12 | Mycobacterium smegmatis | streptomycin |
| P0C0Q9 | model | DNA gyrase subunit A | Staphylococcus epidermidis | ciprofloxacin |
| P0A8M3 | 4HWS; 1TKY; 4HWO; 4P3O; 1FYF; 4P3P; 1QF6; 1EVK; 1EVL; 4HWP; 1KOG; 4HWR; 1TKG; 1TKE; 1TJE | Threonine--tRNA ligase | Escherichia coli (strain K12) | borrelidin |
| O25608 | 3QDL | Oxygen-insensitive NADPH nitroreductase | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) | metronidazole |
| P0A4A3 | model | 30S ribosomal protein S12 | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) | streptomycin |
| P0A5Y7 | model | Enoyl-[acyl-carrier-protein] reductase [NADH] | Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) | isoniazid |
| P42829 | model | Enoyl-[acyl-carrier-protein] reductase [NADH] | Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) | isoniazid |
| O86094 | model | DNA-directed RNA polymerase subunit beta | Legionella pneumophila | rifampicin |
| P17293 | 2OM7; 4V8X; 1TWT | 30S ribosomal protein S12 | Thermus thermophilus | streptomycin |
| Q2G2Q0 | model | DNA gyrase subunit A | Staphylococcus aureus (strain NCTC 8325) | fluoroquinolone |
| P0A7W1 | 5JTE; 4V48; 5ME1; 4V47; 5J5B; 4V54; 4ADV; 5U4J; 5MDZ; 5U4I; 5J88; 5UYQ; 5UYP; 5MDY; 5WDT; 5UYK; 4V89; 5UYM; 5UYL; 5UYN; 2YKR; 5WE6; 5WE4; 5KCS; 4V4Q; 4V4V; 4V4W; 4V4H; 5IT8; 5KCR; 4WOI; 6C4I; 5JC9; 5L3P; 3JA1; 3J9Z; 5NP6; 4V55; 4WWW; 4V57; 4V56; 4V50; 4V53; 4V52; 5MY1; 4WF1; 5H5U; 4V5B; 4V5H; 1M5G; 5O2R; 5WFK; 4V5Y; 5LZE; 5LZD; 5LZF; 5LZA; 5LZC; 5LZB; 1EG0; 4V85; 5MDV; 5MDW; 4U27; 4U26; 4U25; 4U24; 4U20; 5KPS; 5KPV; 5KPW; 5KPX; 5IQR; 3JBU; 4V9P; 3JBV; 6GXP; 6DNC; 4U1V; 6GXO; 4U1U; 5NWY; 4V9C; 4V9D; 4V9O; 5MGP; 3JCJ; 3JCN; 5J91; 3JCD; 3JCE; 6GXN; 6GXM; 5UZ4; 5NO2; 5NO3; 5NO4; 4V69; 5U9F; 4V64; 4V65; 4V66; 5J7L; 5AFI; 6ENU; 4A2I; 4V7V; 4V7U; 4V7T; 4V7S; 5ME0; 3J9Y; 6ENF; 4V7I; 4V7D; 4V7C; 4V7B; 4V7A; 6ENJ; 5JU8; 4V79; 4V78; 4V77; 4V76; 4V75; 4V74; 4V73; 4V72; 4V71; 4V70; 5J8A; 6GWT; 6BU8; 4YBB; 4V6Y; 4V6Z; 4V6T; 4V6V; 4V6P; 4V6Q; 4V6R; 4V6S; 4V6L; 4V6M; 4V6N; 4V6O; 5U9G; 4V6K; 4V6D; 4V6E; 4V6C | 30S ribosomal protein S5 | Escherichia coli (strain K12) | neamycin, spectinomycin |
| A0R607 | 4F4Q; 4G3T; 4AUT; 4G3U | Decaprenylphosphoryl-beta-D-ribose oxidase | Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) | btz043 |
| O33807 | model | Beta-lactamase CTX-M-4 | Salmonella typhimurium | ceftriaxone and aztreonam |
| O52271 | model | DNA-directed RNA polymerase subunit beta | Rickettsia prowazekii (strain Madrid E) | rifampicin |
| Q9RLT9 | model | DNA-directed RNA polymerase subunit beta | Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) | rifampicin |
| P16657 | model | Enoyl-[acyl-carrier-protein] reductase [NADH] FabI | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) | diazaborine |
| P21472 | 6HA1; 6HA8; 3J9W; 5NJT | 30S ribosomal protein S12 | Bacillus subtilis (strain 168) | streptomycin |
| P9WH63 | model | 30S ribosomal protein S12 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | streptomycin |
| O54297 | model | 30S ribosomal protein S4 | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) | streptomycin |
| P60281 | 6CCE; 5VI8; 5VI5; 6CCV; 5TW1 | DNA-directed RNA polymerase subunit beta | Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) | rifampicin |
| A5U8S6 | model | Aspartate 1-decarboxylase | Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) | pyrazinoic acid |
| P37871 | model | DNA-directed RNA polymerase subunit beta' | Bacillus subtilis (strain 168) | streptolydigan |
| Q59622 | model | DNA-directed RNA polymerase subunit beta | Neisseria meningitidis serogroup B (strain MC58) | rifampicin |
| Q50395 | model | Probable arabinosyltransferase B | Mycobacterium smegmatis | ethambutol |
| P21467 | 6HA1; 6HA8; 3J9W; 5NJT | 30S ribosomal protein S5 | Bacillus subtilis (strain 168) | streptomycin |
| P59676 | 5OJ0; 5OAU; 5OJ1; 1PYY; 5OIZ | Penicillin-binding protein 2X | Streptococcus pneumoniae (strain ATCC BAA-255 / R6) | cefotamine |
| P0A0X4 | model | 30S ribosomal protein S12 | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) | streptomycin |
| P0A4L9 | model | DNA gyrase subunit B | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) | novobiocin |
| O34847 | model | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha | Bacillus subtilis (strain 168) | pyrrolidine dione antibiotic cpd2 |
| P63200 | model | 30S ribosomal protein S12 | Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2) | streptomycin |
| P9WJF1 | 4KW5; 4NCR; 4FDP; 4FDN; 4FDO; 4PFA; 4PFD; 4P8L; 4P8P; 4P8T; 4P8Y; 5OEP; 4P8C; 4P8H; 4P8K; 6HF0; 4P8M; 4P8N; 6HF3; 4FF6; 4FEH; 6HEZ | Decaprenylphosphoryl-beta-D-ribose oxidase | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ty38c, tca1, btz043, btz043 and pbtz169 |
| P20831 | 5BS3; 4PLB | DNA gyrase subunit A | Staphylococcus aureus | fluoroquinolone |
| B0SSI2 | model | 30S ribosomal protein S12 | Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris) | streptomycin |
| P63196 | model | 30S ribosomal protein S12 | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) | streptomycin |
| P60723 | 5JTE; 4V48; 5ADY; 4V7S; 4V47; 5GAH; 5GAG; 5GAF; 5GAE; 5GAD; 6GC0; 4WWW; 5MDZ; 5U4I; 3J7Z; 5J88; 5UYQ; 5UYP; 5MDY; 5WDT; 5AKA; 6GC7; 5UYK; 4V89; 5UYM; 5UYL; 5UYN; 5WE6; 5WE4; 5KCS; 4V4Q; 4V4V; 4V4W; 4V4H; 5IT8; 6GC6; 5KCR; 4WOI; 6C4I; 5JC9; 5L3P; 5J5B; 6GBZ; 3JA1; 3J9Z; 5NP6; 4V55; 4V54; 4V57; 4V56; 6GC4; 4V50; 4V53; 4V52; 6GC8; 4WF1; 5H5U; 4V5B; 4V5H; 5O2R; 2RDO; 4V71; 5NCO; 4V5Y; 5LZE; 5LZD; 5LZF; 5LZA; 5LZC; 5LZB; 4CSU; 5WFK; 4V85; 5MDV; 5MDW; 4U27; 4U26; 4U25; 4U24; 4U20; 5KPS; 5KPV; 5KPW; 5KPX; 5IQR; 3JBU; 4V9P; 3JBV; 6GXP; 4U1V; 6GXO; 4U1U; 5NWY; 4V9C; 4V9D; 4V9O; 3J8G; 5MGP; 3JCJ; 3JCN; 3BBX; 5J91; 3JCD; 3JCE; 6GXN; 6GXM; 4V69; 5U9F; 4V64; 4V65; 4V66; 5J7L; 5AFI; 6ENU; 4V7V; 4V7U; 4V7T; 3J5L; 3J9Y; 6ENF; 4V7I; 4V7D; 4V7C; 4V7B; 4V7A; 6ENJ; 5JU8; 4V79; 4V78; 4V77; 4V76; 4V75; 4V74; 4V73; 4V72; 2J28; 4V70; 5J8A; 6GWT; 6BU8; 4YBB; 4V6Y; 4V6Z; 4V6T; 4V6V; 4V6P; 4V6Q; 4V6R; 4V6S; 4V6L; 4V6M; 4V6N; 4V6O; 5U9G; 4V6K; 4V6D; 4V6E; 4UY8; 4V6C | 50S ribosomal protein L4 | Escherichia coli (strain K12) | erythromycin |
| Q97SV4 | model | 50S ribosomal protein L4 | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) | macrolide |
| P9WNL5 | 3PTY | Probable arabinosyltransferase C | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ethambutol |
| P02980 | no data | Tetracycline resistance protein, class B | Escherichia coli | tetracycline |
| P0A4A5 | model | 30S ribosomal protein S12 | Streptomyces lividans | streptomycin |
| P0AG63 | 5JTE; 4V48; 5ME1; 4V47; 5J5B; 4V54; 4ADV; 5MDZ; 5U4I; 5J88; 5UYQ; 5UYP; 5MDY; 5WDT; 5UYK; 4V89; 5UYM; 5UYL; 5UYN; 2YKR; 5WE6; 5WE4; 5KCS; 4V4Q; 4V4V; 4V4W; 4V4H; 5IT8; 5KCR; 4WOI; 6C4I; 5JC9; 5L3P; 3JA1; 3J9Z; 5NP6; 4V55; 4WWW; 4V57; 4V56; 4V50; 4V53; 4V52; 5MY1; 4WF1; 5H5U; 4V5B; 4V5H; 1M5G; 5O2R; 5WFK; 4V5Y; 5LZE; 5LZD; 5LZF; 5LZA; 5LZC; 5LZB; 1EG0; 4V85; 5MDV; 5MDW; 4U27; 4U26; 4U25; 4U24; 4U20; 5KPS; 5KPV; 5KPW; 5KPX; 5IQR; 3JBU; 4V9P; 3JBV; 6GXP; 4U1V; 6GXO; 4U1U; 5NWY; 4V9C; 4V9D; 4V9O; 5MGP; 3JCJ; 3JCN; 5J91; 3JCD; 3JCE; 6GXN; 6GXM; 5NO2; 5NO3; 5NO4; 4V69; 5U9F; 4V64; 4V65; 4V66; 5J7L; 5AFI; 6ENU; 4A2I; 4V7V; 4V7U; 4V7T; 4V7S; 5ME0; 3J9Y; 6ENF; 4V7I; 4V7D; 4V7C; 4V7B; 4V7A; 6ENJ; 5JU8; 4V79; 4V78; 4V77; 4V76; 4V75; 4V74; 4V73; 4V72; 4V71; 4V70; 5J8A; 6GWT; 6BU8; 4YBB; 4V6Y; 4V6Z; 4V6T; 4V6V; 4V6P; 4V6Q; 4V6R; 4V6S; 4V6L; 4V6M; 4V6N; 4V6O; 5U9G; 4V6K; 4V6D; 4V6E; 4V6C | 30S ribosomal protein S17 | Escherichia coli (strain K12) | neamine |
| P0A7S3 | 5JTE; 4V48; 5ME1; 4V47; 5J5B; 4WWW; 4ADV; 5U4J; 5MDZ; 5U4I; 3DEG; 5J88; 5UYQ; 5UYP; 5MDY; 5WDT; 1ZN1; 5UYK; 4U20; 5UYM; 5UYL; 5UYN; 2YKR; 5WE6; 5WE4; 5KCS; 4V4Q; 4V4V; 4V4W; 4V4H; 5IT8; 5KCR; 4WOI; 6C4I; 5JC9; 5L3P; 3JA1; 3J9Z; 5NP6; 4V55; 4V54; 4V57; 4V56; 4V50; 4V53; 4V52; 5MY1; 3EP2; 4WF1; 5H5U; 4V5B; 4V5H; 1M5G; 5O2R; 5WFK; 4V5Y; 5LZE; 5LZD; 5LZF; 5LZA; 5LZC; 5LZB; 3EQ3; 3EQ4; 4V85; 5MDV; 5MDW; 4U27; 4U26; 4U25; 4U24; 4V89; 5KPS; 5KPV; 5KPW; 5KPX; 5IQR; 4V69; 3JBU; 4V9P; 3JBV; 6GXP; 4U1V; 6GXO; 4U1U; 5NWY; 4V9C; 4V9D; 4V9O; 5MGP; 3J0E; 3J0D; 3JCJ; 3JCN; 5J91; 3JCD; 3JCE; 6GXN; 6GXM; 5NO2; 5NO3; 5NO4; 1MJ1; 5U9F; 4V64; 4V65; 4V66; 5J7L; 5AFI; 6ENU; 4A2I; 4V7V; 4V7U; 4V7T; 4V7S; 5ME0; 3J9Y; 6ENF; 4V7I; 4V7D; 4V7C; 4V7B; 4V7A; 6ENJ; 5JU8; 4V79; 4V78; 4V77; 4V76; 4V75; 4V74; 4V73; 4V72; 4V71; 4V70; 5J8A; 6GWT; 6BU8; 4YBB; 4V6Y; 4V6Z; 4V6T; 4V6V; 4V6P; 4V6Q; 4V6R; 4V6S; 4V6L; 4V6M; 4V6N; 4V6O; 5U9G; 4V6K; 4V6D; 4V6E; 4V6C | 30S ribosomal protein S12 | Escherichia coli (strain K12) | streptomycin |
| Q87K03 | no data | Pentapeptide repeat protein VPA0095 | Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) | fluoroquinolone |
| P9WKD3 | 6B6F; 6B6D; 3VFF; 6B6B; 6B6C; 6B6A; 3VFH; 3ZHH; 3M6B; 4EBL; 3N6I; 3NCK; 3DWZ; 3N8S; 3N8R; 6B5Y; 6B5X; 3NY4; 3IQA; 4JLF; 5NJ2; 5OYO; 4X6T; 3N8L; 3NDG; 3NDE; 3N7W; 4QHC; 4Q8I; 3M6H; 4QB8; 4DF6; 4EBP; 3NBL; 4EBN; 3CG5; 6B6E; 3NC8; 2GDN; 6B68; 6B69 | Beta-lactamase | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ampicillin |
| O25608 | 3QDL | rdxA | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) | In strain: ATCC 49503 |
| O52271 | no data | rpoB | Rickettsia prowazekii (strain Madrid E) | In strain: Breinl |
| P00956 | model | ileS | Escherichia coli (strain K12) | 6000-fold increase in Km for isoleucine and 4-fold increase in Km for ATP%2C with no effect on activity |
| P02980 | no data | tetA | Escherichia coli | No change in activity |
| P0A475 | model | rplP | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) | Susceptible to evernimicin |
| P0A6N2 | no data | tufA | Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) | In tufA |
| P0A6N3 | model | tufA | Escherichia coli O157:H7 | In tufA |
| P0A7W1 | 5JTE; 4V48; 5ME1; 4V47; 5J5B; 4V54; 4ADV; 5U4J; 5MDZ; 5U4I; 5J88; 5UYQ; 5UYP; 5MDY; 5WDT; 5UYK; 4V89; 5UYM; 5UYL; 5UYN; 2YKR; 5WE6; 5WE4; 5KCS; 4V4Q; 4V4V; 4V4W; 4V4H; 5IT8; 5KCR; 4WOI; 6C4I; 5JC9; 5L3P; 3JA1; 3J9Z; 5NP6; 4V55; 4WWW; 4V57; 4V56; 4V50; 4V53; 4V52; 5MY1; 4WF1; 5H5U; 4V5B; 4V5H; 1M5G; 5O2R; 5WFK; 4V5Y; 5LZE; 5LZD; 5LZF; 5LZA; 5LZC; 5LZB; 1EG0; 4V85; 5MDV; 5MDW; 4U27; 4U26; 4U25; 4U24; 4U20; 5KPS; 5KPV; 5KPW; 5KPX; 5IQR; 3JBU; 4V9P; 3JBV; 6GXP; 6DNC; 4U1V; 6GXO; 4U1U; 5NWY; 4V9C; 4V9D; 4V9O; 5MGP; 3JCJ; 3JCN; 5J91; 3JCD; 3JCE; 6GXN; 6GXM; 5UZ4; 5NO2; 5NO3; 5NO4; 4V69; 5U9F; 4V64; 4V65; 4V66; 5J7L; 5AFI; 6ENU; 4A2I; 4V7V; 4V7U; 4V7T; 4V7S; 5ME0; 3J9Y; 6ENF; 4V7I; 4V7D; 4V7C; 4V7B; 4V7A; 6ENJ; 5JU8; 4V79; 4V78; 4V77; 4V76; 4V75; 4V74; 4V73; 4V72; 4V71; 4V70; 5J8A; 6GWT; 6BU8; 4YBB; 4V6Y; 4V6Z; 4V6T; 4V6V; 4V6P; 4V6Q; 4V6R; 4V6S; 4V6L; 4V6M; 4V6N; 4V6O; 5U9G; 4V6K; 4V6D; 4V6E; 4V6C | rpsE | Escherichia coli (strain K12) | In strain: B |
| P0ABQ4 | 1DRA; 1DRB; 1DRE; 1JOM; 5UII; 1DRH; 6DFR; 3KFY; 3QYO; 3OCH; 4EIZ; 5DFR; 4FHB; 1RX4; 4KJJ; 1JOL; 5UIO; 2D0K; 5UIH; 1RX5; 1RA2; 1RX7; 1RX6; 1RX1; 1TDR; 1RX3; 1RX2; 2ANO; 2DRC; 1RX9; 1RX8; 4PDJ; 2INQ; 1RC4; 1RA3; 1RA1; 2ANQ; 4GH8; 4NX6; 4NX7; 1RA8; 1RA9; 4DFR; 1RG7; 3R33; 5CCC; 3QYL; 4I13; 4EIG; 5W3Q; 1RE7; 3DRC; 3QL3; 4KJK; 5EAJ; 5CC9; 3DAU; 1DDS; 1DDR; 1RH3; 7DFR; 1DYH; 1DYI; 1DYJ; 5UIP; 4X5J; 4KJL; 4I1N; 4X5I; 1RD7; 4X5H; 4X5G; 1DHJ; 1DHI; 3K74; 1RB3; 1RB2; 4EJ1; 4X5F; 5E8Q; 1RF7; 5UJX | folA | Escherichia coli (strain K12) | No effect |
| P0AEK4 | 1MFP; 1I30; 1DFI; 1DFH; 3PJF; 1LXC; 1DFG; 5CG1; 3PJE; 1LX6; 1QG6; 1D8A; 1C14; 3PJD; 4JX8; 5CFZ; 5CG2; 1QSG; 1I2Z; 4JQC; 2FHS | fabI | Escherichia coli (strain K12) | No effect on substrate reduction |
| P0AES4 | 1ZI0; 4ELY; 1AB4; 2Y3P; 1X75; 3NUH | gyrA | Escherichia coli (strain K12) | In gyrA462%3B resistant to cytotoxic protein CcdB%2C but not to the quinoline antibiotic enoxacin%2C has no effect on DNA supercoiling |
| P0C1U9 | model | parC | Staphylococcus aureus | In strain: FDA 574 |
| P0CE47 | 4PC3; 2HCJ; 4PC7; 1ETU; 3U2Q; 4V69; 5JBQ; 1D8T; 1MJ1; 5I4R; 5I4Q; 3EP2; 5UYQ; 5UYP; 1EFC; 2FX3; 2HDN; 5UYK; 5UYM; 5UYL; 5UYN; 4G5G; 3U6B; 3EQ3; 3U6K; 4Q7J; 3EQ4 | tufA | Escherichia coli (strain K12) | No longer phosphorylated by phage protein doc%2C has no effect on translation |
| P13364 | model | gyrB | Pseudomonas putida (Arthrobacter siderocapsulatus) | In strain: JCM 6156 and PB4 |
| P25397 | 2XVA; 2XVM | tehB | Escherichia coli (strain K12) | No effect on tellurite resistance |
| P30843 | model | basR | Escherichia coli (strain K12) | In strain: ECOR 1%2C ECOR 10%2C ECOR 11%2C ECOR 12%2C ECOR 13%2C ECOR 14%2C ECOR 15%2C ECOR 16%2C ECOR 17%2C ECOR 18%2C ECOR 19%2C ECOR 2%2C ECOR 20%2C ECOR 21%2C ECOR 22%2C ECOR 24%2C ECOR 25%2C ECOR 26%2C ECOR 27%2C ECOR 3%2C ECOR 30%2C ECOR 33%2C ECOR 34%2C ECOR 35%2C ECOR 36%2C ECOR 37%2C ECOR 38%2C ECOR 4%2C ECOR 40%2C ECOR 41%2C ECOR 42%2C ECOR 43%2C ECOR 44%2C ECOR 45%2C ECOR 46%2C ECOR 47%2C ECOR 48%2C ECOR 5%2C ECOR 50%2C ECOR 51%2C ECOR 52%2C ECOR 53%2C ECOR 54%2C ECOR 55%2C ECOR 56%2C ECOR 57%2C ECOR 59%2C ECOR 6%2C ECOR 60%2C ECOR 61%2C ECOR 62%2C ECOR 63%2C ECOR 64%2C ECOR 65%2C ECOR 66%2C ECOR 67%2C ECOR 68%2C ECOR 69%2C ECOR 7%2C ECOR 70%2C ECOR 71%2C ECOR 72%2C ECOR 8 and ECOR 9 |
| P43791 | model | folA | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) | In strain: Isolate R1042 and Isolate R1047 |
| P9WG45 | 3ZKB; 5BTL; 5BTN; 5BTI; 3ZKD; 5BTD; 5BTG; 5BTF; 5BTA; 5BTC; 5BS8; 3IG0; 3M4I; 2ZJT; 3ZM7 | gyrB | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Increased susceptibility to fluoroquinolones%2C half supercoiling activity%2C no fluoroquinolone-induced DNA cleavage (makes sequence more like E |
| P9WG47 | 3UC1; 5BTL; 5BTN; 5BTI; 3ILW; 5BTA; 5BTG; 5BTF; 4G3N; 5BTC; 5BS8; 5BTD; 3IFZ | gyrA | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Increased susceptibility to fluoroquinolones (makes sequence more like E |
| P9WGR1 | 5CP8; 2PR2; 3OF2; 5COQ; 5CPB; 5CPF; 4DRE; 2IDZ; 3FNH; 3FNE; 3FNG; 3FNF; 2AQ8; 3OEW; 3OEY; 2NSD; 5UGU; 5UGT; 5UGS; 1ENY; 4DTI; 4UVG; 4UVE; 4UVD; 4UVI; 4UVH; 2AQH; 2AQI; 2AQK; 4QXM; 4BQP; 4BQR; 1BVR; 1ENZ; 6GH1; 1P45; 1P44; 4BGE; 4OIM; 4BGI; 2B35; 2B37; 2B36; 4OXN; 4OXK; 5G0T; 5G0U; 5G0V; 5G0W; 4OXY; 5G0S; 4U0K; 2H9I; 2NTJ; 4R9S; 4R9R; 5MTR; 5MTP; 5MTQ; 2X22; 4OYR; 2X23; 4D0R; 4D0S; 2IED; 2IEB; 4U0J; 4DQU; 5JFO; 2NV6; 4BII; 4OHU; 1ZID; 4TZK; 4TRJ; 4TRN; 4TRO; 4TZT; 4TRM; 5OIN; 5OIM; 5OIL; 5OIF; 4COD; 5OIT; 2IE0 | inhA | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | No effect on catalytic activity |
| Q06893 | model | vanB | Enterococcus faecalis (strain ATCC 700802 / V583) | In strain: SF300 |
| Q9AIV3 | model | mprF | Staphylococcus aureus | In strain: KSA8 |
| Q9FBG4 | no data | cfr | Staphylococcus sciuri | No change in activity |
| Id | Structure | Gene | Organism | Miscellaneous (Resistance to drug/non-resistant description) |